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by Agustina Fernandez February 24, 2026 8 min read

If you have ever found yourself wondering whether probiotic drops might help your baby’s gassiness, fussiness, or unpredictable digestion, you’re not alone.
More parents than ever are looking into baby probiotics drops as a gentle way to support gut comfort, especially during those early months when digestion is still very much a work in progress.
Below, we will discuss the best infant probiotic drops, what they are, how to use them, and when they might come in handy.
Table of Contents

Probiotic drops are liquid supplements that contain live, beneficial bacteria. These bacteria are similar to the friendly microbes that naturally live in your baby’s digestive tract.
These are helpful because babies are not born with a fully developed gut microbiome. Instead, the balance of bacteria builds gradually after birth and continues to mature throughout infancy and toddlerhood. Feeding method, delivery type, illness, medications, and even environment can all influence how that microbial community develops.
Unlike powders or capsules designed for adults, drops are specifically formulated for infants so they can be given safely and accurately in very small amounts.
While they can be super helpful in supporting digestion, probiotic drops are not meant to replace normal feeding or medical care. They are designed to support gut balance during periods when the digestive system may be under stress or still finding its rhythm.
In the first months of life, your baby’s digestive system is still under construction. The muscles that move food through the gut, the enzymes that help break down milk, and the immune cells that line the intestinal wall are all learning how to work together.
This is one of the main reasons why everyday changes, such as a growth spurt, a feeding adjustment, starting formula, or recovering from a mild illness, can easily lead to gas, unsettled behaviour, irregular stools, or general digestive discomfort. This is where a probiotic for babies can sometimes be helpful.
The gut is home to trillions of bacteria, and when the balance of bacteria is still developing, digestion can be less efficient and more sensitive. Over time, supporting the growth of helpful bacteria can encourage a more stable and resilient gut environment.
A probiotic for babies works by introducing specific strains of beneficial bacteria that are known to behave in helpful ways inside the infant gut. One of the most important strains commonly used in infant supplements is Bifidobacterium lactis . This group of bacteria closely reflects the dominant bacteria naturally found in the gut of breastfed babies. That makes it particularly helpful for formula-fed or combination-fed infants, whose gut microbiome can look slightly different during early development.
Another widely researched strain is Lactobacillus reuteri. This probiotic has been studied extensively in babies, especially in relation to gut comfort and excessive crying associated with colic. Several clinical studies suggest that certain strains of L. reuteri may help reduce crying time in some infants and support more comfortable digestion. Its role appears to be linked to how it influences gut motility and interacts with the intestinal nervous system.
A third commonly used strain in infant formulations is Lactobacillus rhamnosus. This strain has been studied for its ability to reduce colic and its interaction with the gut barrier and immune cells. It is often included to support overall digestive resilience, particularly during periods of change such as illness or antibiotic exposure.
Some modern infant probiotic drops combine several of these strains and pair them with prebiotics, which are small fibres that help feed the beneficial bacteria already present in the gut.
For example, Kendamil drops use a blend of Bifidobacterium lactis, Lactobacillus reuteri, and Lactobacillus rhamnosus, alongside prebiotic FOS. This type of combination is designed to both introduce helpful bacteria and support the growth and activity of your baby’s existing microbiome.
When infants are given probiotics, parents often notice changes gradually, such as more settled feeds, improved comfort after meals, and more predictable bowel movements rather than immediate or dramatic results.
It is important to understand, however, that probiotics are highly strain-specific. Not all probiotics behave the same way in the body. Benefits seen in clinical studies are usually tied to very particular strains, given in specific doses, to specific age groups. This means that results from one product cannot automatically be applied to all probiotic supplements.
Some babies will never need probiotic supplementation. Others may benefit during specific periods of digestive adjustment. A targeted infant probiotic is most often considered when parents are dealing with ongoing functional digestive discomfort.
Let’s look at the most common situations.

Colic is not simply crying. It is persistent, difficult-to-soothe crying in an otherwise healthy baby.
Research increasingly suggests that some colicky infants show differences in gut microbiota composition compared with non-colicky babies. This is one of the reasons probiotic supplementation is now commonly discussed in colic management strategies.
While probiotics will not eliminate all crying, some parents find that a well-selected strain can gently reduce the intensity or frequency of discomfort over time.
Baby gas is extremely common in early infancy. Swallowing air, immature intestinal movement, and the fermentation of undigested carbohydrates can all contribute.
In some babies, probiotic strains that support carbohydrate digestion may help reduce gas production and improve overall comfort.
This is where parents often try probiotics for baby digestion during growth spurts or formula changes.
Constipation in babies is not just about how often they poop; it's also a matter of stool consistency and whether bowel movements appear uncomfortable.
Certain probiotic strains may help soften stools slightly by influencing gut motility and fermentation patterns. This can be especially helpful during feeding transitions, such as switching formula brands or starting solids later in infancy.
However, if constipation is severe, persistent, or associated with poor growth or vomiting, probiotics should not replace medical evaluation.
Short-term diarrhea, particularly after illness or antibiotic use, is among the strongest evidence-based uses of probiotics. In these situations, infant probiotics may help restore microbial balance more quickly as the gut recovers.
There is no single ideal time of day to administer probiotic drops; what matters most is consistency.
Most parents find it easiest to give drops alongside a feed, either directly into the mouth or mixed into milk. This supports regular daily intake and improves tolerance. Whether you choose morning or evening is far less important than ensuring the drops are given consistently over time.
For families using probiotics drops for babies as part of a comfort routine, pairing supplementation with the same feed each day often helps avoid missed doses.
Probiotic drops are usually administered using a pipette or dropper.
They can be given:
Directly into your baby’s mouth
On a clean spoon
Mixed into expressed breast milk
Added to a prepared bottle
If you are using infant probiotics drops, avoid mixing them into very hot liquids, as heat can damage live bacteria. Always follow the manufacturer’s dosage instructions exactly. More is not better when it comes to probiotics.
Most babies do not require probiotics indefinitely. Supplementation is often used during specific periods, such as digestive transitions, recovery from illness, or phases of increased discomfort.
Once symptoms improve and digestion becomes more predictable, many parents gradually stop supplementation and simply observe how their baby responds. If discomfort returns, short-term use can be reconsidered, but in that case, it is best to discuss your concerns with your pediatrician to make sure there isn't a more significant ailment that needs addressing.

When selecting a probiotic supplement for your baby, strain selection matters far more than brand recognition.
A high-quality product should clearly list the full bacterial strain names, specify the number of live organisms per dose, and be formulated specifically for infants. Products that combine probiotics with prebiotics, such as the inclusion of FOS in Kendamil Pro-Comfort, can be particularly helpful in supporting the survival and activity of beneficial bacteria once they reach your baby’s gut.
It is also important to look for products that have been developed with infant safety and tolerability in mind, including appropriate dosing for very young babies and clear guidance for use from birth when applicable.
The best baby probiotic drops will also be free from unnecessary fillers, artificial sweeteners, and maltodextrin. Shelf stability and storage instructions should be clear and easy to follow, especially for families who travel or rely on consistent daily dosing routines.
If you are searching for a probiotic for babies, prioritize products supported by infant-specific research and transparent formulation rather than general adult supplements that have simply been adapted for children.
For many families, probiotic supplementation can be a helpful short-term tool for digestive comfort and microbiome support.
They are not a cure-all. They do not replace appropriate feeding practices or medical evaluation. But when used appropriately, probiotics can play a supportive role in your baby’s digestive development.
Here are some of the most commonly asked questions about probiotics for babies.
Most healthy, full-term babies tolerate probiotic supplementation very well. In the first few days of use, mild gas or temporary changes in stool may occur as the gut microbiome adjusts. These effects typically resolve without intervention. If your baby experiences persistent discomfort, skin reactions, or feeding difficulties after starting supplementation, it is appropriate to stop and consult a healthcare professional.
Improvements are usually gradual. Most parents notice changes within one to three weeks of consistent daily use. This timeline reflects how long it takes for beneficial bacteria to establish themselves and interact with the existing microbiome.
Many probiotic drops, including products formulated from birth such as Kendamil Pro-Comfort, are considered safe for healthy, full-term newborns. For preterm infants or babies with compromised immune systems or complex medical conditions, probiotic use should only be considered with medical guidance. In these cases, individualized advice is essential.
Daily use is appropriate during a defined supplementation period. That said, probiotics are not typically intended as permanent supplements for most infants. If you are using an infant probiotic over several months, it is suggested to review ongoing use with your child’s healthcare provider.
Most infant products are designed for once-daily dosing. Always follow the manufacturer’s instructions and avoid increasing the dose beyond what is recommended.
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Disclaimer: Please be aware that this information is based on general trends in babies, and it is not medical advice. Your doctor should be your first source of information and advice when considering any changes to your child’s formula and when choosing your child’s formula. Always consult your pediatrician before making any decisions about your child’s diet or if you notice any changes in your child. Breastfeeding is the best nutrition for your baby because breast milk provides your child with all the essential nutrients they need for growth and development. Please consult your pediatrician if your child requires supplemental feeding. |
Dr. Agustina Fernandez earned her medical degree from the prestigious Universidad Nacional de Córdoba, Argentina. With a deep-rooted passion for pediatrics, Dr. Fernandez is currently on the path to specializing in children's healthcare. Recently, she has delved into the vital field of infant nutrition. Her research interests include breastfeeding, infant formula, and baby food in little ones’ formative years. Dr. Fernandez's commitment to this area of study underscores her dedication to ensuring the health and well-being of children from their earliest days.
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